Translation

I just did a quick read of a fabulous position paper by Bartek Rajwa and my mentor Mario Roederer. Have a look! Lost in Translation: Harmonizing Terminology and Defining Mathematical Tools for Panel Optimization - Rajwa - Cytometry Part A - Wiley Online Library Some thoughts: In short, the thesis is that the community needs to be more exact in the terms that we use when developing panels. Bartek and Mario argue that currently used terms and approaches are mysterious and i

OK, getting on a soapbox here. I just want my data. For all of the standardization and formatting that the FCS file standard is providing, when I open files up in flow cytometry analysis software, a myriad of annoyances present themselves... variously, at one point or another: 1) parameters show up out of order 2) parameters aren't labeled with the reagent or dye 3) only the scatter parameters show up etc etc A skeptic might say, "maybe it's just a you issue" or "maybe it's

Here's the conclusion of the documentary on Precision Medicine by Biocompare. The text they wrote for YouTube summarizes it well: " In the final segment of our documentary on precision medicine, Leroy Hood, Sharon Terry, Michael Snyder, and Pratip Chattopadhyay discuss how new science and technology are improving healthcare from reactive treatment to proactive, personalized, and preventive care. They reflect on advances in genomics, phenomics, artificial intelligence, and we

The team at Biocompare put together a wonderful documentary about technologies that play a role in precision medicine. I am featured in two parts, the one about flow cytometry and the conclusion. Here's the video about flow cytometry! Click on the link below! https://youtu.be/Uqmaed9cbS4?si=IdaudyKa8XCOaaFn

In part I, we took a quick look at technologies that analyze plasma proteins, the most accessible, but noisiest and least informative about mechanism, amongst the sample types that we examine. Here, we quickly review technologies that examine cells. These are the technologies I grew up on, so they are fun to write about. An important note: This post focuses on technologies that study cells by the proteins they express. *Molecular cytometry is a generic term for CITE-Seq an

Do you remember multiple choice tests? The hardest questions offered options "d) some of the above" and "e) all of the above." But you never got an "it depends" option, at least until now. So, just like Jeopardy, here's the question answered by "it depends." Which technology is best for immune monitoring and biomarker discovery? Let's explore assays that study serum or plasma , in a simple and clear way, with a special focus on impact. I've color-coded the discussion points